other material
confidence high
sentiment positive
materiality 0.75
Cabaletta Bio presents preconditioning-free clinical data and automated manufacturing data for rese-cel at ASGCT 2026
Cabaletta Bio, Inc.
- Two of four pemphigus vulgaris patients at lowest PC-free dose maintained drug-free responses through 6 months.
- No dose-limiting toxicities or neurotoxicity; one patient had grade 1 cytokine release syndrome.
- First two autoimmune patients dosed with rese-cel manufactured on Cell Shuttle met all release specs with similar PK/PD.
- Higher-dose PC-free data expected 2H26; initial SLE data at lowest dose expected 1H26 at EULAR 2026 Congress.