secwatch.observer — SEC 8-K summary ====================================== Issuer: Mirum Pharmaceuticals, Inc. (MIRM) CIK: 0001759425 Form: 8-K Filed at: 2026-02-25T23:59:59+00:00 Accession: 0001759425-26-000010 Event type: earnings Sentiment: positive Materiality: 0.80 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Mirum Pharma 2025 sales $521M (+55% YoY); guides 2026 $630-650M; multiple pipeline readouts in 2026 -------------------------------------------------------------------------------- - 2025 net product sales $521.3M, up from $336.4M in 2024 (+55% YoY). LIVMARLI US sales $244.7M (+69% YoY). - 2026 guidance: global net product sales $630-650M, reflecting continued growth. - Pipeline catalysts: Volixibat VISTAS (PSC) topline Q2 2026; Livmarli EXPAND data Q4 2026; Brelovitug HDV data H2 2026. - Completed acquisition of Bluejay Therapeutics for brelovitug; raised $268.5M in private placements. - Cash and investments $391.4M as of Dec 31, 2025; operating expenses $543.4M (incl. $95M non-cash). Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1759425/000175942526000010/0001759425-26-000010-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1759425/000175942526000010/mirm-20260225.htm HTML page: https://secwatch.observer/filing/0001759425-26-000010 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer