other material
confidence high
sentiment neutral
materiality 0.60
Instil Bio doses first patient with ITIL-306 CoStAR-TIL in Phase 1 NSCLC trial
Instil Bio, Inc.
- First patient dosed in Phase 1 study of ITIL-306, a CoStAR-engineered TIL therapy targeting FRα in non-small cell lung cancer.
- ITIL-306 designed to enhance TIL activity in tumor microenvironment and eliminate need for high-dose IL-2.
- Initial clinical data from dose escalation cohorts expected in 2023.
- Phase 1 open-label multicenter study also includes ovarian and renal cell carcinoma patients.