earnings
confidence high
sentiment negative
materiality 0.60
Instil Bio reports 2022 net loss of $223M; cash runway beyond 2026; ITIL-306 phase 1 in 2H 2023
Instil Bio, Inc.
2023-Q1 EPS reported
-$0.44
- Cash & marketable securities $260.9M (Dec 31, 2022) vs $454.1M in 2021; cash runway beyond 2026 with <$10M quarterly burn from 2H 2023.
- Net loss $223.2M in 2022 ($1.72/share) vs $156.8M ($1.48/share) in 2021; restructuring charge $23.2M.
- Discontinued ITIL-168 program Dec 2022 over manufacturing issues; prioritized ITIL-306 with anticipated UK MHRA CTA clearance 2H 2023.
- Initial ITIL-306 phase 1 clinical data expected in 2024; consolidated R&D ops to Manchester, UK; seeking lease/sale of Tarzana facility.