---
schema_version: "secwatch.filing_event.v1"
accession: "0001816431-26-000061"
form_type: "8-K"
ticker: "QSI"
cik: "0001816431"
company_name: "Quantum-Si Inc"
filed_at: "2026-09-29T00:29:05+00:00"
generated_at: "2026-10-12T13:39:56.542696+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# Quantum-Si interim Proteus data: 30x more alignments, 4.8x lower false discovery rate vs Platinum Pro

## Summary
- Proteus delivered a median 4,094,411 alignments per single chamber versus 135,901.5 for Platinum Pro (30.1x), identifying all six control peptides in every run.
- Median false discovery rate was 1.36% on Proteus vs 6.58% on Platinum Pro, a 4.8-fold improvement; the developmental kit detects 18 amino acids.
- In a 24-protein panel not previously sequenced on either platform, Proteus detected all 24 proteins vs an average of 20.3 on Platinum, and 269,864 amino acids per run vs 63,366 (4.3x).
- Company projects a full four-chamber Proteus run could yield roughly 60x more alignments than a two-chamber Platinum Pro run; instrument, consumable and software remain unoptimized.
- CEO Jeff Hawkins presents the interim results at World HUPO 2026 in Singapore on Sept. 29, 2026 at 12:15 p.m. SGT in Room 330.

## SEC filing metadata
- accession: 0001816431-26-000061
- form_type: 8-K
- ticker: QSI
- cik: 0001816431
- company_name: Quantum-Si Inc
- filed_at: 2026-09-29T00:29:05+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1816431/000181643126000061/0001816431-26-000061-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1816431/000181643126000061/qsi-20260928.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001816431-26-000061
- JSON: https://secwatch.observer/filing/0001816431-26-000061.json
- Plain text: https://secwatch.observer/filing/0001816431-26-000061.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.