---
schema_version: "secwatch.filing_event.v1"
accession: "0001818331-21-000002"
form_type: "8-K"
ticker: "WGS"
cik: "0001818331"
company_name: "GeneDx Holdings Corp."
filed_at: "2021-10-14T23:59:59+00:00"
generated_at: "2026-06-28T20:54:32.165600+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.45
calibrated_materiality_score: 0.45
confidence: "high"
source: SEC EDGAR
---

# Sema4 President and COO James Coffin to take 90-day medical leave; CFO and CBO to assume duties

## Summary
- James Coffin, President and COO, expects 90-day disability leave starting October 2021.
- CFO Isaac Ro and Chief Business Officer Kareem Saad will perform Coffin's functions during leave.
- Company does not anticipate adverse impact on financial performance or corporate objectives.

## SEC filing metadata
- accession: 0001818331-21-000002
- form_type: 8-K
- ticker: WGS
- cik: 0001818331
- company_name: GeneDx Holdings Corp.
- filed_at: 2021-10-14T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.45
- calibrated_materiality_score: 0.45
- confidence: high
- sec_items: 5.02
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1818331/000181833121000002/0001818331-21-000002-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1818331/000181833121000002/smfr-20211008.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001818331-21-000002
- JSON: https://secwatch.observer/filing/0001818331-21-000002.json
- Plain text: https://secwatch.observer/filing/0001818331-21-000002.txt

## Key facts
- Executive change
  James Coffin changed role as President and Chief Operating Officer at GeneDx Holdings Corp..
  - Action: Taking 90-day medical leave
  - Role: President and Chief Operating Officer
  source text: James Coffin, Ph.D. the Company’s Treasurer from January 2021 to March 2021, and President and Chief Operating Officer since 2017, expects to be on short-term disability leave for medical reasons for approximately 90 days, commencing sometime in October 2021 (the “Leave”).
  evidence_url: https://www.sec.gov/Archives/edgar/data/1818331/000181833121000002/0001818331-21-000002-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.