{"schema_version":"secwatch.filing_event.v1","accession":"0001824293-25-000167","form_type":"8-K","ticker":"GRI","cik":"0001824293","company_name":"GRI Bio, Inc.","filed_at":"2025-12-10T23:59:59+00:00","discovered_at":"2026-05-14T18:02:40.636346+00:00","generated_at":"2026-05-16T13:40:01.831573+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.85,"calibrated_materiality_score":0.85,"confidence":"high","headline":"GRI Bio announces positive Phase 2a topline results for GRI-0621 in IPF","bullets":["Primary endpoint met: GRI-0621 well tolerated with no drug-related severe/serious adverse events; no GI increase vs placebo.","Biomarkers improved: type VI collagen remodeling shifted from fibrogenic (+10%) to fibrolytic (-7%), suggesting fibrosis resolution.","FVC improved: placebo-adjusted increase of 99ml (139ml with standard of care); 39% of GRI-0621 subjects gained FVC vs 80% of placebo declined.","Type IV collagen remodeling shifted to neutral (0%) vs fibrolytic (-16%) in placebo, indicating alveolar basement membrane repair."],"urls":{"canonical":"https://secwatch.observer/filing/0001824293-25-000167","json":"https://secwatch.observer/filing/0001824293-25-000167.json","markdown":"https://secwatch.observer/filing/0001824293-25-000167.md","text":"https://secwatch.observer/filing/0001824293-25-000167.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1824293/000182429325000167/0001824293-25-000167-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1824293/000182429325000167/val-20251210.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-16T13:40:01.831573+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}