---
schema_version: "secwatch.filing_event.v1"
accession: "0001827635-26-000036"
form_type: "8-K"
ticker: "MANE"
cik: "0001827635"
company_name: "Veradermics, Inc"
filed_at: "2026-10-19T13:06:14+00:00"
generated_at: "2026-10-19T13:07:07.189730+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.85
calibrated_materiality_score: 0.85
confidence: "high"
source: SEC EDGAR
---

# Veradermics VDPHL01 hits all Phase 3 '304' endpoints; TAHC up 28.6-36.4 hairs/cm² vs 6.6 placebo

## Summary
- Study '304' randomized 536 males with mild-to-moderate pattern hair loss to VDPHL01 8.5mg once-daily, twice-daily or placebo; all primary and secondary endpoints met (p<0.0001).
- Non-vellus target area hair count rose 28.6 hairs/cm² (QD) and 36.4 hairs/cm² (BID) at Month 6 vs 6.6 for placebo; significant separation from placebo seen as early as Month 2.
- 55.7% (QD) and 68.7% (BID) reported 'improved' or 'much improved' hair coverage on AAIRS vs 15.0% placebo; investigator IGA rated 78.4% and 82.7% improved.
- No treatment-related SAEs and no cardiac AESIs; hypertrichosis was the only TEAE >5% with an imbalance (2.2% QD, 9.0% BID); peripheral edema 2.8%/4.5% vs 0.6% placebo.
- Part B 12-month data from Study '302' expected later in 2026; female pattern hair loss Study '306' topline anticipated in H1 2027.

## SEC filing metadata
- accession: 0001827635-26-000036
- form_type: 8-K
- ticker: MANE
- cik: 0001827635
- company_name: Veradermics, Inc
- filed_at: 2026-10-19T13:06:14+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.85
- calibrated_materiality_score: 0.85
- confidence: high
- sec_items: 7.01, 8.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1827635/000182763526000036/0001827635-26-000036-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1827635/000182763526000036/mane-20261019.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001827635-26-000036
- JSON: https://secwatch.observer/filing/0001827635-26-000036.json
- Plain text: https://secwatch.observer/filing/0001827635-26-000036.txt

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.