secwatch.observer — SEC 8-K summary ====================================== Issuer: Barinthus Biotherapeutics plc. (BRNS) CIK: 0001828185 Form: 8-K Filed at: 2025-03-20T23:59:59+00:00 Accession: 0001828185-25-000018 Event type: earnings Sentiment: neutral Materiality: 0.75 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Barinthus Bio FY2024 net loss $61.1M; cash runway into 2027; VTP-1000 data Q3 2025 -------------------------------------------------------------------------------- - Net loss of $61.1M ($1.55 per share) vs $73.3M in 2023; goodwill impairment of $12.2M. - Cash $112.4M at Dec 31, 2024, down from $142.1M; expected cash runway into 2027. - Revenue $15.0M from Vaxzevria royalties (no future payments expected). - Lead candidate VTP-1000 (celiac disease) Phase 1 AVALON trial; single ascending dose data expected Q3 2025. - VTP-300 for CHB achieved 8 participants with HBsAg loss, 2 functional cures; Phase 2b data due Q2 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1828185/000182818525000018/0001828185-25-000018-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1828185/000182818525000018/brns-20250320.htm HTML page: https://secwatch.observer/filing/0001828185-25-000018 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer