---
schema_version: "secwatch.filing_event.v1"
accession: "0001829126-25-009754"
form_type: "8-K"
ticker: "NTHI"
cik: "0001979414"
company_name: "NEONC TECHNOLOGIES HOLDINGS, INC."
filed_at: "2025-12-05T23:59:59+00:00"
generated_at: "2026-05-16T14:21:18.789617+00:00"
event_type: "other_material"
sentiment: "positive"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# NeOnc raises $1M from Saad Naja; AI study shows ultrasound boosts NEO100 against brain tumors

## Summary
- Issued 111,732 shares at $8.95 to Saad Naja, raising gross proceeds of ~$1M for working capital.
- Preclinical collaboration with USC (bioRxiv) shows NEO100 combined with focused ultrasound enhances tumor killing in glioblastoma, medulloblastoma, meningioma, and metastases.
- AI-trained platform using 200+ molecular descriptors identified NEO100 as a leading sonosensitizer; 3D-bioprinted organoids validated results in days vs. weeks.
- Results support moving NEO100-plus-ultrasound into future clinical trials for multiple primary and metastatic brain tumors.
- CEO Heshmatpour says findings expand NEO100's commercial and clinical opportunity beyond current indications.

## SEC filing metadata
- accession: 0001829126-25-009754
- form_type: 8-K
- ticker: NTHI
- cik: 0001979414
- company_name: NEONC TECHNOLOGIES HOLDINGS, INC.
- filed_at: 2025-12-05T23:59:59+00:00
- event_type: other_material
- sentiment: positive
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 1.01, 3.02, 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1979414/000182912625009754/0001829126-25-009754-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1979414/000182912625009754/neonctechnologies_8k.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0001829126-25-009754
- JSON: https://secwatch.observer/filing/0001829126-25-009754.json
- Plain text: https://secwatch.observer/filing/0001829126-25-009754.txt

## Key facts
- Equity Issuances
  NEONC TECHNOLOGIES HOLDINGS, INC. issued 111,732 shares of common stock to Saad Naja for $8.95 per share.
  - Security: common stock
  - Shares: 111,732 shares
  - Purchaser: Saad Naja
  - Consideration: $8.95 per share
  source text: issue and sell 111,732 shares (the “Shares”) of common stock, $0.0001 par value per share of the Company (the “Common Stock”). The per share purchase price of the Shares is $8.95, which represents the closing price of the Common Stock as reported on the Nasdaq Capital Market on November 28, 2025. The Shares were sold for approximately $1 million. The
  evidence_url: https://www.sec.gov/Archives/edgar/data/1979414/000182912625009754/0001829126-25-009754-index.htm
- Material Agreements
  NEONC TECHNOLOGIES HOLDINGS, INC. entered into Securities Purchase Agreement with Saad Naja valued at approximately $1 million (effective 2025-12-01).
  - Action: entry
  - Agreement: equity purchase
  - Counterparty: Saad Naja
  - Value: approximately $1 million
  - Effective: 2025-12-01
  source text: On December 1, 2025, NeOnc Technologies Holdings, Inc. (the “Company”) entered into a Securities Purchase Agreement (the “Agreement”) with Saad Naja (the “Investor”) to issue and sell 111,732 shares (the “Shares”) of common stock, $0.0001 par value per share of the Company (the “Common Stock”).
  evidence_url: https://www.sec.gov/Archives/edgar/data/1979414/000182912625009754/0001829126-25-009754-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.