{"schema_version":"secwatch.filing_event.v1","accession":"0001831283-23-000071","form_type":"8-K","ticker":"LIANY","cik":"0001831283","company_name":"LianBio","filed_at":"2023-04-26T23:59:59+00:00","discovered_at":"2026-05-14T18:03:40.975914+00:00","generated_at":"2026-06-16T13:34:48.936306+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.85,"calibrated_materiality_score":0.85,"confidence":"high","headline":"LianBio's mavacamten meets primary endpoint in Phase 3 EXPLORER-CN trial; NDA accepted with Priority Review in China","bullets":["EXPLORER-CN met primary endpoint: Valsalva LVOT gradient improvement from baseline to week 30 vs placebo (p<0.001).","All secondary endpoints met, including resting LVOT gradient, NYHA class improvement, KCCQ-CSS, and LV mass index.","Safety consistent with prior studies; no LVEF <50% requiring dose interruption.","NDA for mavacamten accepted with Priority Review by China NMPA for symptomatic oHCM.","LianBio to host analyst event May 1 to discuss topline data and China market opportunity."],"urls":{"canonical":"https://secwatch.observer/filing/0001831283-23-000071","json":"https://secwatch.observer/filing/0001831283-23-000071.json","markdown":"https://secwatch.observer/filing/0001831283-23-000071.md","text":"https://secwatch.observer/filing/0001831283-23-000071.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1831283/000183128323000071/0001831283-23-000071-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1831283/000183128323000071/lian-20230426.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-16T13:34:48.936306+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}