other material
confidence high
sentiment positive
materiality 0.65
Context reports preliminary Phase 2 data for ONA-XR: 4-month PFS rate of 44% in metastatic breast cancer
Context Therapeutics Inc.
- 4-month progression-free survival (PFS) rate of 44% in ER+, HER2- metastatic breast cancer patients in SMILE trial.
- ONA-XR combined with fulvestrant showed favorable safety and tolerability in second- or third-line setting.
- Previously disclosed endometrial cancer data showed 4-month PFS rate of 77% with anastrozole combination.
- ELONA Phase 1b/2 trial combining ONA-XR with elacestrant; Phase 1b data expected Q4 2023.