other material
confidence high
sentiment negative
materiality 0.80
Context Therapeutics discontinues ONA-XR, prioritizes CTIM-76; 2022 net loss $14.8M
Context Therapeutics Inc.
- Discontinued ONA-XR due to elevated LFTs in 3 patients and competitive landscape; exploring strategic options.
- Focusing on CTIM-76 (CLDN6 x CD3 bispecific) for solid tumors; IND expected Q1 2024.
- Cash $35.5M at Dec 31, 2022, down from $49.7M; cash runway extended into late 2024.
- 2022 net loss $14.8M vs $10.5M in 2021; R&D $7.1M, G&A $7.8M.
- CTIM-76 preclinical data at AACR April 17, 2023; investor R&D webinar same day.