{"schema_version":"secwatch.filing_event.v1","accession":"0001842952-23-000082","form_type":"8-K","ticker":"CNTX","cik":"0001842952","company_name":"Context Therapeutics Inc.","filed_at":"2023-10-31T23:59:59+00:00","discovered_at":"2026-05-14T18:03:30.971972+00:00","generated_at":"2026-06-09T04:57:27.923475+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.8,"calibrated_materiality_score":0.8,"confidence":"high","headline":"Context Therapeutics reports preclinical CTIM-76 data showing tumor regressions; IND on track for Q1 2024","bullets":["CTIM-76 induced dose-proportional tumor regressions and was well tolerated in xenograft models.","CTIM-76 showed ten-fold higher potency than AMG-794 in in vitro cytotoxicity and cytokine activation assays.","CTIM-76 retained activity across low to high CLDN6 expression, unlike TORL-1-23 which depended on high expression.","IND filing for CTIM-76 planned for late Q1 2024.","Approximately 70,000 US patients with CLDN6-positive metastatic solid tumors have no approved targeted treatment."],"urls":{"canonical":"https://secwatch.observer/filing/0001842952-23-000082","json":"https://secwatch.observer/filing/0001842952-23-000082.json","markdown":"https://secwatch.observer/filing/0001842952-23-000082.md","text":"https://secwatch.observer/filing/0001842952-23-000082.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1842952/000184295223000082/0001842952-23-000082-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1842952/000184295223000082/cntx-20231031.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-09T04:57:27.923475+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}