other material
confidence high
sentiment positive
materiality 0.65
Context Therapeutics doses first patient in Phase 1 trial of CTIM-76 for CLDN6-positive cancers
Context Therapeutics Inc.
- First patient dosed in Phase 1 open-label trial of CTIM-76 (CLDN6 x CD3 bispecific antibody).
- Trial targets CLDN6-positive advanced/metastatic ovarian, endometrial, and testicular cancers.
- Study expected to enroll up to 70 patients; initial data anticipated first half of 2026.
- CEO Martin Lehr highlights the milestone as key pipeline advancement.
- Company presented at SITC 2024 supporting first-in-human dose selection.