other material
confidence high
sentiment positive
materiality 0.55
Context Therapeutics doses first patient in Phase 1 trial of CT-95 bispecific antibody
Context Therapeutics Inc.
- CT-95 is a mesothelin x CD3 T cell engaging bispecific antibody targeting MSLN-expressing cancers.
- Second TCE bispecific to enter clinic in 2025 following CTIM-76 (Claudin 6 x CD3) earlier this year.
- Phase 1 open-label dose escalation and expansion study for advanced solid tumors (ovarian, pancreatic, lung, mesothelioma).
- Initial data for CT-95 Phase 1 trial expected in mid-2026.
- CEO Martin Lehr highlights expansion of clinical pipeline and leadership in TCE therapies.