earnings
confidence high
sentiment neutral
materiality 0.60
Centessa Q4 net loss $43.2M; cash $393.6M; SerpinPC, LB101, ORX750 progress
Centessa Pharmaceuticals plc
- Cash and cash equivalents $393.6M as of Dec 31, 2022; expected to fund operations into 2026.
- Net loss attributable to ordinary shareholders $43.2M for Q4 2022 vs $60.8M in Q4 2021.
- SerpinPC registrational program for hemophilia B ongoing; PRESent-5 enrolling; PRESent-2/3 dosing expected in 2023.
- First subject dosed in Phase 1/2a trial of LB101 (PD-L1xCD47 LockBody) for solid tumors.
- ORX750 nominated as product candidate for narcolepsy; preclinical data expected at scientific meeting in 2023.