other material
confidence high
sentiment positive
materiality 0.65
Senti Bio partners with Celest for SENTI-301A development in China; up to $156M milestones
Senti Biosciences, Inc.
- Celest to lead clinical development and manufacturing of SENTI-301A in mainland China; first patient expected 1H 2024.
- Senti Bio retains all commercialization rights outside mainland China, Hong Kong, Macau, and Taiwan.
- Senti eligible for up to $156M in milestone payments plus tiered royalties on potential sales.
- SENTI-301A is an off-the-shelf CAR-NK cell therapy targeting GPC3-expressing hepatocellular carcinoma.
- Pilot trial will enroll 9 patients across two dose cohorts to assess safety and efficacy.