{"schema_version":"secwatch.filing_event.v1","accession":"0001854270-25-000062","form_type":"8-K","ticker":"SNTI","cik":"0001854270","company_name":"Senti Biosciences, Inc.","filed_at":"2025-05-06T23:59:59+00:00","discovered_at":"2026-05-14T18:02:50.171713+00:00","generated_at":"2026-05-22T14:02:34.971158+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"positive","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Senti Bio reports Q1 2025 net loss $14.1M; SENTI-202 Phase 1 shows 4 of 7 cCR with MRD negativity","bullets":["Net loss of $14.1M ($1.41 per share) for Q1 2025; cash and equivalents $33.8M as of March 31.","Phase 1 SENTI-202 data: 4 of 7 patients achieved composite CR (3 CR, 1 CRh); all MRD negative by local standard of care.","Preliminary RP2D set at 1.5 x 10^9 CAR NK cells given on Days 0,7,14 in 28-day cycles after lymphodepletion.","Responses ongoing from 4+ to 8+ months; 3 patients received bone marrow transplant after SENTI-202.","R&D expenses $9.3M (up $0.5M YoY); G&A expenses $7.1M (down $0.4M YoY)."],"urls":{"canonical":"https://secwatch.observer/filing/0001854270-25-000062","json":"https://secwatch.observer/filing/0001854270-25-000062.json","markdown":"https://secwatch.observer/filing/0001854270-25-000062.md","text":"https://secwatch.observer/filing/0001854270-25-000062.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1854270/000185427025000062/0001854270-25-000062-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1854270/000185427025000062/snti-20250506.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-22T14:02:34.971158+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}