other material
confidence high
sentiment neutral
materiality 0.50
Mineralys completes enrollment in Explore-CKD Phase 2 trial of lorundrostat; topline data expected Q2 2025
Mineralys Therapeutics, Inc.
- Phase 2 trial evaluating lorundrostat for hypertension in Stage 2-3b CKD with albuminuria on stable ACEi/ARB and SGLT2i.
- Primary endpoint: change from baseline in systolic BP at week 4 vs placebo; exploratory endpoint includes UACR change.
- Third trial to recently complete enrollment, alongside Target-HTN, Advance-HTN, and Explore-OSA.
- Topline data anticipated in Q2 2025.