secwatch.observer — SEC 8-K summary ====================================== Issuer: Zymeworks Inc. (ZYME) CIK: 0001937653 Form: 8-K Filed at: 2025-05-08T23:59:59+00:00 Accession: 0001937653-25-000026 Event type: earnings Sentiment: positive Materiality: 0.65 Item codes: 2.02, 7.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Zymeworks Q1 revenue $27.1M, net loss narrows to $22.6M; cash runway into 2H-2027 -------------------------------------------------------------------------------- - Revenue of $27.1M (vs. $10.0M in Q1 2024); net loss of $22.6M improved from $31.7M. - Cash resources $321.6M; combined with anticipated milestones expected to fund operations into 2H-2027. - Partner Jazz received EMA positive opinion for zanidatamab in HER2+ BTC; final decision pending. - Recognized $14.0M GSK milestone (paid Apr 2025) and $3.1M Daiichi Sankyo milestone; additional milestones remain. - Appointed Dr. Sabeen Mekan as SVP Clinical Development; six preclinical posters presented at AACR. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1937653/000193765325000026/0001937653-25-000026-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1937653/000193765325000026/zyme-20250508.htm HTML page: https://secwatch.observer/filing/0001937653-25-000026 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer