{"schema_version":"secwatch.filing_event.v1","accession":"0001937653-26-000046","form_type":"8-K","ticker":"ZYME","cik":"0001937653","company_name":"Zymeworks Inc.","filed_at":"2026-08-06T20:09:05+00:00","discovered_at":"2026-08-06T20:11:31.330108+00:00","generated_at":"2026-08-06T20:11:58.317870+00:00","sec_items":["2.02","7.01","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.75,"calibrated_materiality_score":0.75,"confidence":"high","headline":"Zymeworks Q2 net loss $45M; PDUFA for zanidatamab Aug 25; Theravance acquisition on track","bullets":["Net loss of $45.0M in Q2 2026 vs net income of $2.3M in Q2 2025; revenue fell to $4.6M from $48.7M.","Cash and marketable securities $322.5M as of June 30, 2026; repurchased $49.4M of shares under new $125M program.","PDUFA target date Aug 25, 2026 for zanidatamab in 1L HER2+ GEA; potential $250M U.S. approval milestone.","Acquisition of Theravance Biopharma expected to close 2H 2026, adding YUPELRI profit share and ~$60M annualized cash flow.","R&D expenses down 20% YoY to $27.4M; G&A up to $19.3M on higher stock comp."],"urls":{"canonical":"https://secwatch.observer/filing/0001937653-26-000046","json":"https://secwatch.observer/filing/0001937653-26-000046.json","markdown":"https://secwatch.observer/filing/0001937653-26-000046.md","text":"https://secwatch.observer/filing/0001937653-26-000046.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1937653/000193765326000046/0001937653-26-000046-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1937653/000193765326000046/zyme-20260806.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-08-06T20:11:58.317870+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}