earnings
confidence high
sentiment neutral
materiality 0.65
ACELYRIN reports FY 2023 net loss of $381.6M; cash $721.3M; pipeline progress with izokibep and lonigutamab
ACELYRIN, Inc.
- Net loss $381.6M in 2023 vs $64.8M in 2022; R&D expenses $355.9M including $123.1M IPR&D from ValenzaBio acquisition.
- Cash, equivalents and marketable securities $721.3M expected to fund operations into 2026 through late-stage registrational studies.
- Positive Phase 1/2 data for lonigutamab (subcutaneous anti-IGF-1R) in thyroid eye disease with rapid proptosis improvements at 3 weeks.
- Phase 2b/3 trial of izokibep met primary endpoint ACR50 at 16 weeks with high statistical significance in psoriatic arthritis; HS Phase 3 topline data expected H2 2024.
- Appointed Agnes Lee as SVP IR and Corporate Communications; Lynn Tetrault joined Board in December 2023.