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Tonix announces preclinical data for TNX-1700 in gastric cancer models published in Cancer Cell
Tonix Pharmaceuticals Holding Corp.
- mTNX-1700 plus anti-PD-1 increased survival and decreased metastases in gastric cancer animal models vs anti-PD-1 alone.
- Treatment associated with activation of CD8+ T cells and limiting neutrophil-mediated immune evasion.
- Human version TNX-1700 (hTFF2-HSA) is in preclinical development for gastric and colorectal cancers.
- Collaboration with Columbia University's Medical School; paper titled 'A CXCR4 Partial Agonist, Improves Immunotherapy...'.
- Data support further development of TNX-1700 to overcome resistance to anti-PD-1 immunotherapy.
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