{"schema_version":"secwatch.filing_event.v1","accession":"0001999371-25-008900","form_type":"8-K","ticker":"TNXP","cik":"0001430306","company_name":"Tonix Pharmaceuticals Holding Corp.","filed_at":"2025-07-10T23:59:59+00:00","discovered_at":"2026-05-14T18:02:43.974621+00:00","generated_at":"2026-05-18T08:43:39.240559+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.65,"calibrated_materiality_score":0.65,"confidence":"high","headline":"Tonix TNX-801 vaccine data: 100,000-fold less virulent, s.c. route protective","bullets":["TNX-801 is up to 100,000-fold less virulent than licensed vaccinia in interferon receptor knockout mice.","Subcutaneous administration yields equivalent protection to percutaneous route; company plans s.c. product first.","Single dose protected all vaccinated macaques from lethal Clade I mpox challenge without lesions.","Rabbit models remained fully protected for 14 months post single dose.","Company to advance TNX-801 into clinic via subcutaneous delivery for mpox and smallpox prevention."],"urls":{"canonical":"https://secwatch.observer/filing/0001999371-25-008900","json":"https://secwatch.observer/filing/0001999371-25-008900.json","markdown":"https://secwatch.observer/filing/0001999371-25-008900.md","text":"https://secwatch.observer/filing/0001999371-25-008900.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1430306/000199937125008900/0001999371-25-008900-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1430306/000199937125008900/tonix-8k_071025.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-18T08:43:39.240559+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}