other material
confidence high
sentiment positive
materiality 0.55
Tonix licenses exclusive worldwide rights to TNX-4900 for neuropathic pain from Rutgers University
Tonix Pharmaceuticals Holding Corp.
- Licensed exclusive worldwide rights to TNX-4900 (S1R antagonist) from Rutgers University for chronic neuropathic pain.
- TNX-4900: Ki=7.5 nM, >100-fold selectivity over Sigma-2, oral bioavailability ~28%.
- Preclinical efficacy in diabetic and chemotherapy-induced neuropathic pain models without tolerance or motor impairment.
- Company plans IND-enabling studies; no financial terms disclosed.