secwatch.observer — SEC 8-K summary ====================================== Issuer: Alto Neuroscience, Inc. (ANRO) CIK: 0001999480 Form: 8-K Filed at: 2024-05-14T23:59:59+00:00 Accession: 0001999480-24-000020 Event type: earnings Sentiment: neutral Materiality: 0.55 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Alto Neuroscience Q1 net loss $13.4M; cash $205.9M; pipeline on track for multiple readouts -------------------------------------------------------------------------------- - Net loss $13.4M vs $7.3M YoY; R&D expenses $10.0M, G&A $4.4M, both up on clinical study costs and public company expenses. - Cash and equivalents $205.9M as of March 31, 2024; expects to fund operations into 2027. - Initiated Phase 2 study of ALTO-203 in MDD with anhedonia; reported positive Phase 1 data for transdermal ALTO-101 with improved tolerability. - Phase 2b studies of ALTO-100 and ALTO-300 in MDD enrolling; topline data for ALTO-100 expected 2H 2024, ALTO-300 1H 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1999480/000199948024000020/0001999480-24-000020-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1999480/000199948024000020/alto-20240514.htm HTML page: https://secwatch.observer/filing/0001999480-24-000020 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer