secwatch.observer — SEC 8-K summary ====================================== Issuer: Alto Neuroscience, Inc. (ANRO) CIK: 0001999480 Form: 8-K Filed at: 2025-03-20T23:59:59+00:00 Accession: 0001999480-25-000024 Event type: earnings Sentiment: neutral Materiality: 0.65 Item codes: 2.02, 5.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Alto Neuroscience FY2024 net loss $61.4M; cash $169M; two directors departing ----------------------------------------------------------------------------- - Net loss $61.4M for FY2024 vs $36.3M in 2023; R&D expense $47M, G&A $21.6M. - Cash and equivalents $169M as of Dec 31, 2024; expected to fund operations into 2028. - Directors Jeff Chen and Maha Radhakrishnan will not stand for re-election at 2025 annual meeting; board size to shrink from 7 to 5. - ALTO-300 Phase 2b MDD trial interim analysis positive; topline results expected mid-2026. - ALTO-203 Phase 2 MDD trial enrollment complete; topline data expected Q2 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1999480/000199948025000024/0001999480-25-000024-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1999480/000199948025000024/alto-20250317.htm HTML page: https://secwatch.observer/filing/0001999480-25-000024 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer