{"schema_version":"secwatch.filing_event.v1","accession":"0001999480-25-000035","form_type":"8-K","ticker":"ANRO","cik":"0001999480","company_name":"Alto Neuroscience, Inc.","filed_at":"2025-05-14T23:59:59+00:00","discovered_at":"2026-05-14T18:02:50.661653+00:00","generated_at":"2026-05-21T10:49:23.518595+00:00","sec_items":["2.02","5.07","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Alto Neuroscience Q1 net loss $15.2M; cash $161.3M; key trial readouts on track","bullets":["Net loss of $15.2M for Q1 2025 vs $13.4M in Q1 2024; R&D expense flat at $10.0M.","Cash, cash equivalents and restricted cash of $161.3M as of March 31, 2025, expected to fund operations into 2028.","ALTO-203 Phase 2 POC MDD trial topline data expected in Q2 2025; ALTO-101 Phase 2 CIAS data in H2 2025.","ALTO-300 Phase 2b MDD trial data expected mid-2026; ALTO-100 Phase 2b BPD trial data H2 2026.","At annual meeting, stockholders reelected Husseini Manji as Class I director and ratified Deloitte as auditor."],"urls":{"canonical":"https://secwatch.observer/filing/0001999480-25-000035","json":"https://secwatch.observer/filing/0001999480-25-000035.json","markdown":"https://secwatch.observer/filing/0001999480-25-000035.md","text":"https://secwatch.observer/filing/0001999480-25-000035.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1999480/000199948025000035/0001999480-25-000035-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1999480/000199948025000035/alto-20250513.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-21T10:49:23.518595+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}