earnings
confidence high
sentiment positive
materiality 0.60
Sionna Therapeutics Q2 net loss $18.1M; positive Phase 1 data for NBD1 stabilizers
Sionna Therapeutics, Inc.
2025-Q2 EPS
reported -$980.00
vs consensus -$0.57
▼ miss
(-173014.3%)
- Net loss $18.1M in Q2 2025 vs $8.6M in Q2 2024; R&D expenses $15.4M.
- Cash and equivalents $337.3M as of June 30, 2025; funding expected into 2028.
- Positive Phase 1 data for SION-719 and SION-451: well tolerated, exceeded PK targets.
- Phase 2a trial of SION-719 as add-on to CF standard of care on track for H2 2025; topline data mid-2026.
- Phase 1 dual combination trial of SION-451 with galicaftor and SION-109 on track for H2 2025; data mid-2026.
item 2.02item 9.01