other material
confidence high
sentiment negative
materiality 0.85
LENZ Therapeutics, Inc. (LENZ): restructuring charge — Graphite Bio discontinues sickle cell gene therapy nula-cel, cuts workforce 50%, explores strategic alternatives
LENZ Therapeutics, Inc.
- Discontinues development of nula-cel for sickle cell disease; exploring external continuation.
- Reduces workforce by approximately 50%; expects severance costs of ~$4.9M in Q2 2023.
- Chief Business Officer and Chief Scientific Officer to depart in Q2 2023.
- Preliminary unaudited cash, equivalents, and marketable securities of ~$283.5M as of Dec 31, 2022.
- Will continue early-stage non-genotoxic conditioning program; board approved restructuring.