other material
confidence high
sentiment positive
materiality 0.60
Acrivon doses first patient in Phase 1 trial of WEE1/PKMYT1 inhibitor ACR-2316
Acrivon Therapeutics, Inc.
- First patient dosed two quarters ahead of original timeline for ACR-2316 Phase 1 trial in solid tumors.
- ACR-2316 advanced from initial lead to Phase 1 in 15 months using AP3 platform.
- Initial clinical data from monotherapy dose optimization expected in 2H 2025.
- Trial assesses safety, tolerability, MTD, RP2D, PK, and anti-tumor activity per FDA Project Optimus.