other material
confidence high
sentiment positive
materiality 0.80
Assembly Biosciences reports positive interim Phase 1a results for ABI-1179 in recurrent genital herpes
ASSEMBLY BIOSCIENCES, INC.
- ABI-1179 had a half-life of ~4 days and high exposure across 50mg-300mg doses, supporting once-weekly oral dosing.
- ABI-1179 was well-tolerated with no serious adverse events and all treatment-emergent AEs mild and unrelated.
- Company plans to move directly into Phase 1b, running concurrently with Phase 1b of ABI-5366.
- Interim Phase 1b data for both ABI-1179 and ABI-5366 anticipated in fall 2025.
- ABI-1179 contributed by Gilead Sciences under the Assembly Bio-Gilead collaboration.