Organovo Holdings renames to VivoSim Labs, emerges from stealth to target FDA animal testing phase-out

VivoSim Labs, INC.

Effective April 24, 2025, Organovo Holdings changed its name to VivoSim Labs, Inc. with new ticker symbol VIVS on Nasdaq.
In conjunction with the name change, VivoSim issued a press release announcing emergence from stealth mode to provide NAM models for liver and intestinal toxicology.
The FDA announced on April 10, 2025 a plan to phase out animal testing requirements, representing a potential >$10B market opportunity for VivoSim's non-animal technologies.
VivoSim’s NAMkind liver model achieved industry-best correlation with known clinical failures, aiming to reduce clinical trial failures and cut drug development costs by 50%.
The company's NAMkind intestine models offer novel readouts for drug candidate selection, targeting reduction of patient side effects from chemotherapy.

Key facts

Extracted from this filing and checked against the source text.

Governance Changes SEC 8-K Item 5.03/5.05/5.06 confidence 0.9

VivoSim Labs, INC.: Changed company name from Organovo Holdings, Inc. to VivoSim Labs, Inc. via Certificate of Fourth Amendment to Certificate of Incorporation, effective April 24, 2025 at 12:01 a.m. Eastern Time, no stockholder approval required under DGCL (effective 2025-04-24).

Change: charter amendment
Effective: 2025-04-24

Exact text from the filing

Effective at 12:01 a.m. (Eastern Time) on April 24, 2025, Organovo Holdings, Inc., a Delaware corporation (the “Company”), changed its name to VivoSim Labs, Inc. (the “Name Change”) by filing a Certificate of Fourth Amendment (the “Certificate of Amendment”) to its Certificate of Incorporation, as amended (the “Certificate of Incorporation”), with the Secretary of State of the State of Delaware on April 23, 2025.

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Governance Changes SEC 8-K Item 5.03/5.05/5.06 confidence 0.9

VivoSim Labs, INC.: Amended and restated Amended and Restated Bylaws to reflect the corporate name change to VivoSim Labs, Inc., effective April 24, 2025, with no other changes (effective 2025-04-24).

Change: bylaw amendment
Effective: 2025-04-24

Exact text from the filing

effective April 24, 2025, the Company amended and restated its Amended and Restated Bylaws (the “Bylaws”) to reflect the Name Change (the “A&R Bylaws”).

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VivoSim Labs, INC. filing history →

Source: SEC EDGAR

accession 0000950170-25-057685

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