Annovis Bio publishes Posiphen PK comparison across species in Biomolecules

Annovis Bio, Inc.

Publication in Biomolecules compares Posiphen pharmacokinetics across mouse, rat, dog, and human samples.
Posiphen reaches peak plasma concentration quickly, with high brain and CSF absorption.
Drug metabolizes into N1-norposiphen and N8-norposiphen; rapid clearance in plasma but longer retention in brain/CSF.
Absorption, distribution, metabolism, and excretion similar in healthy volunteers and Alzheimer's/Parkinson's patients.
CEO Maria Maccecchini states publication consolidates years of research for a holistic view of Posiphen.

This headline and bullets were generated automatically by deepseek-v4-flash:cloud@v2 from the public filing. Read the source on SEC.gov before relying on any specific claim. Not investment advice. See methodology for how this pipeline works.