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confidence medium
sentiment neutral
materiality 0.55
NanoViricides says NV-387 and NV-387-remdesivir expected to be effective against Ebola Bundibugyo strain in DRC
NANOVIRICIDES, INC.
- NV-387 is broad-spectrum antiviral entering Phase II for Mpox in DRC.
- NV-387-remdesivir is an oral formulation shown in animal models; PLOS ONE paper published.
- Encapsulation protects remdesivir from metabolism, improving efficacy per company.
- Company has a clinical site in DRC for Mpox; public health responders to decide on Ebola.
- Remdesivir was tested in prior Ebola trials but efficacy not established; antibodies approved only for Zaire strain.