other material
confidence high
sentiment positive
materiality 0.70
Pelareorep data at AACR: 62% ORR in pancreatic cancer; TLS formation in breast cancer
ONCOLYTICS BIOTECH INC
- GOBLET cohort 1: 62% objective response rate in first-line mPDAC, more than double historical chemotherapy alone.
- Patients with immune activation signature had median PFS 7.5 months vs 5.6 months for those without.
- AWARE-1 breast cancer study: pelareorep drove tertiary lymphoid structure formation in select patients.
- Pelareorep stimulated RAS-specific T-cell clones in gastrointestinal cancers, presented at a future meeting.