John McAdory
appointed John McAdory as Chief Operating Officer of the Company
Highest-materiality recent filing
Oncolytics appoints Steve Glover to board, promotes John McAdory to COO
Steve Glover appointed to board effective June 1, 2026; he chaired Ambrx during its $2B J&J acquisition.
Initial data in solid tumor model shows greater anti-tumor activity with pelareorep+RAS inhibitor vs either alone.
Data from GOBLET (advanced pancreatic cancer) and AWARE-1 (early-stage breast cancer) to be presented at ASCO 2026 May 29-June 2.
Oncolytics reports 19.5-month median DOR in 2L RAS-mutant MSS mCRC; triples ORR vs SOC
Pelareorep-based combo shows median duration of response 19.5 months in 2L KRAS-mutant MSS mCRC, vs historical 4–6 months.
Oncolytics secures FDA alignment on pivotal anal cancer study for pelareorep
FDA agreed on a randomized controlled pivotal trial design for pelareorep in post-first-line metastatic SCAC, targeting accelerated and full approval.
Oncolytics Biotech enters ATM agreement for up to $75M common stock offering
Agreement with Jefferies LLC allows sale of up to $75M in common stock at market prices.
Oncolytics schedules Type C FDA meeting for pelareorep single-arm study in anal cancer
FDA meeting set for April 16, 2026 to discuss single-arm pivotal study of pelareorep + checkpoint inhibitor in SCAC.
Redomestication from Canada to Nevada completed; common stock continues trading on Nasdaq under ONCY.
Oncolytics completes continuance to BC; expects Nevada domestication by March 31
First step completed March 17: continuance from Alberta to British Columbia under BCBCA.
Pelareorep data at AACR: 62% ORR in pancreatic cancer; TLS formation in breast cancer
GOBLET cohort 1: 62% objective response rate in first-line mPDAC, more than double historical chemotherapy alone.
Randomized Phase 2 study (REO 033) of pelareorep + bevacizumab + FOLFIRI vs bevacizumab + FOLFIRI in 30 patients per arm.
Oncolytics prioritizes SCAC and CRC registration studies; GOBLET enrollment closed
Concluded enrollment in GOBLET gastrointestinal study; now focusing on registrational studies in squamous cell anal cancer (SCAC) and metastatic colorectal cancer (CRC).
FDA Fast Track Designation for pelareorep + bevacizumab + FOLFIRI in second-line KRAS-mutant MSS metastatic colorectal cancer.
Oncolytics appoints EVP John McAdory and VP Biostatistics Yujun Wu, grants inducement awards
John McAdory named EVP Strategy & Operations; previously VP Clinical Ops at CG Oncology (Nasdaq: CGON).
Oncolytics shareholders OK continuance to BC and domestication to Nevada
Continuance from Alberta to British Columbia approved: 85.21% in favor.
GOBLET Cohort 4: 4/14 evaluable third-line anal cancer patients responded (ORR 29%), 2 CRs, 2 PRs; median DOR ~17 months vs historical ~10%.
appointed John McAdory as Chief Operating Officer of the Company
appointed Stephen Glover as the ninth director of the Board
Max materiality 0.85 · Median 0.65 · Most common event other_material