other material
confidence high
sentiment positive
materiality 0.70
Insmed unveils four new research platforms; targets 6 INDs by 2025; DMD gene therapy trial in 2023
INSMED Inc
- Gene therapy with targeted AAV delivery; DMD clinical trial to start 2023, muscle biopsy data expected H1 2024.
- RNA end-joining (REJ) technology targets Stargardt disease; IND submission expected by end of 2024.
- Protein deimmunization platform (DbD) using AI to enable redosable gene therapy and therapeutic proteins.
- Proprietary algae-based manufacturing platform for AAV capsid production; $500K investment from CureDuchenne Ventures.
- Expects at least six IND applications across platforms by end of 2025.