earnings
confidence high
sentiment positive
materiality 0.75
Q3 2022 XPOVIO sales up 20% YoY; net loss narrows to $0.45/share; guidance reaffirmed
Karyopharm Therapeutics Inc.
2022-Q3 EPS reported
-$1.60
revenue$123,494,000
- Total revenue $36.1M (-4% YoY); XPOVIO net product revenue $32.0M (+20% YoY).
- Net loss $36.3M ($0.45 per share) vs $51.8M ($0.69) in Q3 2021; cash $150.1M.
- Reaffirmed FY2022 guidance: total revenue $155-165M, XPOVIO $120-130M.
- Initiated Phase 3 selinexor maintenance in TP53 wild-type endometrial cancer; topline 2024.
- Phase 1 selinexor+ruxolitinib in myelofibrosis shows SVR35 at 79% at week 12; updated data at ASH.