other material
confidence high
sentiment negative
materiality 0.90
Kezar ends lupus trial after fatal SAEs, adopts poison pill to block $1.10 bid
Kezar Life Sciences, Inc.
- Discontinued PALIZADE Phase 2b in lupus nephritis after 4 Grade 5 SAEs (1 placebo); 84 patients enrolled.
- PORTOLA Phase 2a in autoimmune hepatitis continues; topline data due H1 2025.
- Board rejected Concentra's $1.10/share bid; adopted rights plan (10%/15% threshold, expires Oct 17, 2025).
- Preliminary cash ~$148M as of Sep 30, 2024; company says cash runway extended.
- Concentra accumulated 9.9% of KZR; grandfathered but cannot increase without triggering rights.