earnings
confidence high
sentiment positive
materiality 0.70
Wave Life Sciences Q1 2025 net loss $46.9M; pipeline progress in obesity, AATD, DMD, HD
Wave Life Sciences Ltd.
2025-Q1 EPS reported
-$0.29
revenue$9,175,000
- Net loss of $46.9M vs $31.6M prior year; revenue $9.2M (down from $12.5M). Cash $243.1M, runway into 2027.
- Obesity: dosing complete in first two INLIGHT cohorts for WVE-007; clinical data expected 2H 2025.
- AATD: RestorAATion-2 dosing at 200 mg Q2W and 400 mg single dose; data on multiple cohorts due 3Q and fall 2025.
- DMD: Positive 48-week FORWARD-53 data with 3.8 sec improvement in TTR vs natural history; NDA submission planned 2026.
- HD: IND submission expected 2H 2025 for potentially registrational Phase 2/3 study of WVE-003.