earnings
confidence high
sentiment neutral
materiality 0.65
TScan Therapeutics Q4 net loss $23M; cash $152.4M; FDA clears TSC-102 INDs; plans Phase 3 trial Q2 2026
TScan Therapeutics, Inc.
- Net loss $23.0M in Q4 2025 vs $35.8M Q4 2024; revenue $2.6M vs $0.7M.
- Cash and equivalents $152.4M as of Dec 31, 2025; funds operations into H2 2027.
- FDA cleared INDs for TSC-102-A01 and TSC-102-A03 targeting CD45 for heme malignancies post-HCT.
- Enrollment completed in Cohort C of ALLOHA heme trial with commercial-ready manufacturing; initial data due Q2 2026.
- Discontinued solid tumor PLEXI-T trial; advancing in vivo TCR-T engineering and autoimmunity programs.