Acrivon Therapeutics Q4/FY2025 net loss $19M/$77.9M; cash $118.6M; ACR-368 52% cORR in serous EC

Acrivon Therapeutics, Inc.

Net loss Q4 $19.0M, FY $77.9M; cash and securities $118.6M expected to fund into Q2 2027.
ACR-368 Phase 2b showed 52% confirmed ORR in serous endometrial cancer; Arm 3 enrolling, Arm 4 to start H1 2026.
Completed exploratory Arm 2 (ACR-368 + ULDG) in biomarker-negative EC; objectives met with favorable tolerability.
ACR-2316 Phase 1 data shows tumor shrinkage in SCLC and squamous NSCLC; IND for ACR-6840 planned Q4 2026.
Launched wholly-owned CLIA lab for companion diagnostic development.

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