Taysha reports FY2025 net loss $109M; TSHA-102 pivotal trial dosing on track to complete Q2 2026

Taysha Gene Therapies, Inc.

Net loss $109.0M ($0.34/share) vs $89.3M ($0.36) in 2024; R&D expenses rose to $86.4M.
Cash $319.8M as of Dec 31, 2025; raised $50M via ATM in Q4; expects funding into 2028.
Dosed multiple Rett patients in REVEAL pivotal trial; enrollment advancing, on track to complete dosing in Q2 2026.
FDA cleared ASPIRE trial in patients aged 2 to <4 yrs; alignment on CMC and data pooling for BLA submission.
TSHA-102 generally well tolerated; no treatment-related SAEs or DLTs as of March 2026 data cutoff.

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