CRSP shareholders approve 2026 equity plan, re-elect all directors at AGM

On June 4, 2026, at the Annual Meeting, the shareholders of the Company approved amendments to the articles of association of the Company (the “Articles of Association”) as described in the Company’s Proxy Statement. The Company’s amended and restated Articles of Association become effective upon registration in the Commercial Register in the canton of Zug, Switzerland on or about June 5, 2026, subject to the approval by the Swiss Federal Commercial Authority.

The endorsement of the 2025 Compensation Report was approved on a non-binding basis. The results of the non-binding vote were as follows: FOR AGAINST ABSTAIN BROKER NON-VOTES NUMBER 39,906,651 8,704,469 143,733 22,498,855

The discharge of the members of the Company's Board of Directors and the Executive Committee from personal liability for their activities during the year ended December 31, 2025 was approved. The results of the vote were as follows: FOR AGAINST ABSTAIN BROKER NON-VOTES NUMBER 48,379,678 262,761 112,414 22,498,855

The proposal to carry forward the net loss resulting from the appropriation of financial results was approved. The results of the vote were as follows: FOR AGAINST ABSTAIN BROKER NON-VOTES NUMBER 70,554,606 415,599 283,503 0

Ali Behbahani, M.D., H. Edward Fleming, Jr., M.D., John T. Greene and Briggs W. Morrison, M.D. were each duly re-elected as members of the Company’s Compensation Committee of the Board of Directors. The results of the election were as follows: NOMINEE FOR AGAINST ABSTAIN BROKER NON-VOTES Ali Behbahani, M.D. 35,458,908 13,198,641 97,304 22,498,855 H. Edward Fleming Jr., M.D. 46,322,476 2,341,513 90,864 22,498,855 John T. Greene 46,319,646 2,326,146 109,061 22,498,855 Briggs W. Morrison, M.D. 45,317,635 3,329,265 107,953 22,498,855

Samarth Kulkarni, Ph.D., Ali Behbahani, M.D., Maria Fardis, Ph.D., H. Edward Fleming Jr., M.D., Simeon J. George, M.D., John T. Greene, Katherine A. High, M.D., Sandesh Mahatme, LL.M., Briggs W. Morrison, M.D., Christian Rommel, Ph.D. and Douglas A. Treco, Ph.D. were each duly re-elected as members of the Company’s Board of Directors and Samarth Kulkarni, Ph.D. was duly re-elected as the chairman of the Company’s Board of Directors. The results of the election were as follows: NOMINEE FOR AGAINST ABSTAIN BROKER NON-VOTES Samarth Kulkarni, Ph.D. 47,043,987 1,628,226 82,640 22,498,855 Ali Behbahani, M.D. 35,498,392 13,174,523 81,938 22,498,855 Maria Fardis, Ph.D. 47,804,457 874,207 76,189 22,498,855 H. Edward Fleming Jr., M.D. 46,977,636 1,686,127 91,090 22,498,855 Simeon J. George, M.D. 47,435,748 1,225,519 93,586 22,498,855 John T. Greene 46,876,367 1,793,109 85,377 22,498,855 Katherine A. High, M.D. 47,779,619 899,787 75,447 22,498,855 Sandesh Mahatme, LL.M. 46,268,964 2,405,580 80,30

The Swiss management report, the consolidated financial statements and the statutory financial statements of the Company for the year ended December 31, 2025 were approved. The results of the vote were as follows: FOR AGAINST ABSTAIN BROKER NON-VOTES NUMBER 70,716,663 288,652 248,393 0