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confidence high
sentiment positive
materiality 0.60
Genprex licenses NYU patent for Reqorsa gene therapy in mesothelioma; TUSC2 down in 84%
Genprex, Inc.
- Exclusive patent license with NYU Langone Health for Reqorsa (quaratusugene ozeplasmid) to treat mesothelioma.
- TUSC2 tumor suppressor gene is downregulated in 84% of mesotheliomas; Reqorsa delivers TUSC2.
- Preclinical data showed decreased cell proliferation/invasion and increased apoptosis in all four MPM cell lines.
- Genprex formed a Mesothelioma Clinical Advisory Board of four leading researchers to guide the program.
- About 3,000 new US cases/yr; life expectancy 18 months, 3-year survival rate 23% with treatment.