other_material
confidence high
sentiment positive
materiality 0.60
Telomir-1 restores MASPIN and RASSF1A tumor suppressors in prostate cancer models
Telomir Pharmaceuticals, Inc.
- Telomir-1 reversed DNA hypermethylation to reactivate MASPIN and RASSF1A in aggressive prostate cancer models.
- MASPIN is a natural defense protein blocking invasion and promoting chemotherapy sensitivity; RASSF1A regulates cell cycle and metastasis suppression.
- Dose-dependent reduction in RASSF1A methylation; stronger effect when combined with chemotherapy.
- Company continues IND-enabling studies for Telomir-1.
item 8.01