Highest-materiality recent filing
Telomir-Zn dose-dependently improved survival, reduced hepatic copper burden and liver injury biomarkers (ALT, AST, bilirubin) in zebrafish Wilson's disease model.
FDA cleared IND for lead candidate Telomir-Zn in advanced/metastatic triple-negative breast cancer.
Telomir Pharmaceuticals completes acquisition of TELI, consolidating global rights to Telomir-1
Acquired 100% of TELI for 34,389,710 restricted shares of Telomir common stock to former TELI shareholders.
Telomir Pharmaceuticals submits IND to FDA for Telomir-1 in metastatic triple-negative breast cancer
IND submitted March 31, 2026 for oral Telomir-Zn (Telomir-1) in advanced/metastatic TNBC.
Telomir regains Nasdaq compliance on annual meeting requirement
Received letter from Nasdaq on March 30, 2026 confirming compliance with Rule 5620(a).
TELO shareholders approve acquisition of Teli Pharma and increase share reserve to 11.5M
Acquisition of Teli Pharmaceuticals approved; issuance of >20% new shares authorized.
Near-complete tumor cell mortality in MDA-MB-468 (Basal-A/EGFR-high) TNBC cells at 72h.
Telomir Pharmaceuticals Reports Preclinical Data on Telomir-Zn Modulating Metal Balance
Telomir-Zn induced rapid intracellular zinc increase and labile ferrous iron reduction within 30 minutes in preclinical studies.
Received Nasdaq notice on Jan 8, 2026 for failure to hold annual meeting within 12 months of fiscal year end (Rule 5620(a)).
Telomir-1 reduces tumor growth and metastases in aggressive TNBC models in preclinical study
Telomir-1 showed statistically significant reductions in primary tumor growth in two of three aggressive TNBC zebrafish xenograft models.
CEO Erez Aminov received a 2025 short-term incentive payout of $400,000 for operational and financing achievements.
No treatment-related adverse or dose-limiting toxicities observed across cardiovascular, respiratory, phototoxicity, and repeat-dose safety studies in rats and dogs.
Telomir Pharma reports Telomir-1 reduces PSA in prostate cancer cells in dose-related manner
Telomir-1 reduced PSA levels in dose-related manner in androgen-responsive human prostate cancer cells (LNCaP) in vitro.
Telomir-1 produced dose-dependent reduction in viability of human HL60 leukemia cells (aggressive AML model).
Telomir Pharmaceuticals director Craig Eagle resigns from board, effective Nov 14, 2025
Craig Eagle resigned from the Board of Directors on November 14, 2025, effective immediately.
Telomir-1 outperforms FDA-approved DFO in reducing intracellular iron in preclinical study
Telomir-1 reduced intracellular Fe²⁺ in human keratinocytes in dose- and time-dependent manner at low-micromolar concentrations.
Telomir-1 reduces DNA methylation of CASP8 and GSTP1 in aggressive prostate cancer model
Telomir-1 decreased DNA methylation of CASP8 (apoptosis) and GSTP1 (detoxification) genes at Day 21, vs vehicle and chemo.
Telomir signs binding LOI to acquire TELI, consolidating worldwide rights to Telomir-1
Acquires all TELI shares via stock-for-stock exchange; exchange ratio based on third-party valuation.
Telomir Pharma reports Telomir-1 kills pancreatic cancer cells in vitro; plans further studies
Telomir-1 reduced survival of aggressive human pancreatic cancer (PANC-1) cells in concentration-dependent manner.
Telomir-1 selectively kills triple-negative breast cancer cells in lab studies
Telomir-1 produced concentration-dependent reduction in TNBC cell survival; iron addition reversed effect, confirming iron-dependent mechanism.
Telomir-1 restores MASPIN and RASSF1A tumor suppressors in prostate cancer models
Telomir-1 reversed DNA hypermethylation to reactivate MASPIN and RASSF1A in aggressive prostate cancer models.
Telomir-1 inhibits KDM5 demethylase families in vitro, expanding epigenetic targeting
Telomir-1 inhibits KDM5A, KDM5B, and KDM5C in vitro, blocking silencing of tumor suppressor genes.
Telomir reports preclinical data: Telomir-1 reactivates CDKN2A, beats rapamycin and chemo
New data in PC3 human prostate cancer xenografts shows Telomir-1 inhibits DNA hypermethylation of CDKN2A.
Telomir Pharmaceuticals raises $2.9M via block sale of 1.55M shares at $1.87/share
Sold 1,550,000 shares of common stock to institutional investors at $1.87 average price.
Telomir reports in vitro data: Telomir-1 inhibits UTX and modestly targets Tankyrases
Telomir-1 potently inhibits UTX (KDM6A), a histone demethylase linked to cancer, aging, neurodegeneration.
Telomir Pharmaceuticals Announces In Vitro Data Showing Telomir-1 Inhibits Key Epigenetic Enzymes
Telomir-1 inhibited JMJD3, FBXL10, and FBXL11 histone demethylase enzymes in a Eurofins Discovery study.
Telomir-1 increased mitochondrial energy (WST-1 assay) and reduced ROS under basal and stress conditions.
Telomir Pharmaceuticals sells 1.1M shares in block sales, raises ~$2.9M
Sold 1,100,000 shares at avg price $2.6045 (premium to prior close) to institutional investors.
In PC3 xenograft model, Telomir-1 fully reversed STAT1 hypermethylation after 21-day oral daily dosing.
Telomir Pharmaceuticals announces positive preclinical data for Telomir-1 in progeria cell lines
Telomir-1 significantly increased cell viability in human HGPS cells under basal and metal-toxic conditions.
Telomir-1 shows dose-dependent reversal of Wilson's disease symptoms in animal model
Up to 4-5x reduction in episodic tremor events; normalization of swim and exploratory behavior.
Telomir-1 preclinical study in Werner Syndrome model shows 100% survival, reverses epigenetic aging
Oral Telomir-1 restored healthy DNA methylation at two CpG island regions, resetting the epigenetic clock.
Telomir Pharmaceuticals announces BIO 2025 participation and preclinical progress for Telomir-1
Telomir will participate in the BIO International Convention 2025 in Boston from June 16-19, 2025, with scheduled partnering meetings.
Telomir Pharmaceuticals reports Telomir-1 restores vision in AMD animal model
Telomir-1 improved central vision response and motion detection in AMD zebrafish model.
Telomir Pharmaceuticals raises $3M via premium equity sale from largest shareholder
$3 million raised via direct investment by Bayshore Trust (largest shareholder) at $3.00/share, 18% premium to $2.54 close.
Telomir Pharmaceuticals appoints Alan Weichselbaum as CFO; prior CFO Michelle Yanez departs
Michelle Yanez and Telomir mutually agreed to her resignation as CFO, Treasurer, Secretary effective May 16, 2025; no disagreement.
Effective May 16, 2025, Michelle Yanez and the Company mutually agreed to release Ms. Yanez from her position as Chief Financial Officer, Treasurer and Secretary of Telomir Pharmaceuticals, Inc. (the “Company”), effective on that date.
On May 15, 2025, the Company entered into an Employment Agreement (the “Employment Agreement”) with Mr. Weichselbaum to serve as chief financial officer of the Company beginning on May 19, 2025 (the “Start Date”).
Max materiality 0.95 · Median 0.60 · Most common event other_material