other_material
confidence high
sentiment positive
materiality 0.60
Telomir Pharma reports Telomir-1 reduces PSA in prostate cancer cells in dose-related manner
Telomir Pharmaceuticals, Inc.
- Telomir-1 reduced PSA levels in dose-related manner in androgen-responsive human prostate cancer cells (LNCaP) in vitro.
- Also associated with reductions in cellular energy metabolism and viability in the same study.
- In prior PC3 xenograft mouse model, Telomir-1 reduced tumor volume as single agent; full reduction with paclitaxel combo without mortality.
- Paclitaxel alone achieved full tumor reduction but had high mortality; Telomir-1 combo showed no treatment-related deaths.
- Company advancing IND-enabling activities for planned IND submission across oncology and aging-related conditions.
item 8.01